MY EXPERIENCES WITH GENERAL CELLULAR AND NEURAL CELLULAR PATHOLOGY IN A CASE BASED BLENDED LEARNING ECOSYSTEM'S CBBLE

 Myself tejaswini, young enthusiastic medical student welcoming to my medical cases blog journey 

The first case that i have seen in the course of medicine is in my 3rd semester where the patient was lying on the bed and he looked so weak and when I approached the patient  he complained of fever since 2 days . He is also having body aches, headache and loss of appetite  I was so fasinatate to learn the pathophysiology of fever and causes and how it makes us physically and mentally weak.

And the case was

https://www.blogger.com/blog/post/edit/5638447817479559920/2371950410185238935

Through this case I learned the types of fever pattern and which can lead to diagnose a case through clinical approach  and how to make fever charts and diagnosis of fever based on type of raise wbc count .raised lymphocytes indicate viral fever and raised granulocytes indicate bacterial cause of fever. 

 Fever caused by virus would be sudden and high grade and would not last more than 1 week where as fever caused by bacteria would last more than a week 

Ideal sites to measure temperature like to measure core body temperature rectum and to measure surface body temperature arm pit is ideal and correction to be done to  get accurate temperature 

Another interesting, most common case that seen is patient with yellow discoloration of eyes with eye colour urine since 1week

https://dvntejaswinirollno40.blogspot.com/2022/08/35-yrs-old-m-with-yellow-discoloration.html

Through these case i learned about

1.IMPORTANCE OF LFT?

2.jaudice pathogenesis and how alcohol induces hepatitis?

Alchol is converted into acetaldehyde which can bind to liver cell protein forming neoantigen and leading to inflammation

And also metabolism of Alchol generate hydrogen which cinvert NAD TO NADH which increase redox potential inhibits fatty acid oxidation and gluconeogenesis, promoting fat accumulation in the liver 

3.learned about approach to jaudice case, how to differentiate different type of jaudice and diffential diagnosis

Clinically

 hemolytic jaudice - lemon yellow colour jaundice, mild in nature, stool and urine color normal

Hepatocellular - orange yellow color jaundice, moderate, stool color normal, urine color dark

Obstructive jaundice - 

Greenish yellow jaundice, deep in depth of jaundice where stool color light, urine color dark

4. etiopathogenesis of cirrhosis and hepatic encephalopathy and how it affects patient sensorium

20Y FEMALE WITH SLE:

A 20 yr old female came to general medicine felt with complaints of headache, neck pain and vomiting.

Patient presentation:Pt was asymptomatic 3 days back then she developed neck pain. Vomitings since 1 day with 4 to 5 episodes per day, non bilious type.Headache  with facial puffiness since 1 day which is of frontal type.

By investigations that are carried out there is elevated blood urea and alkaline phosphatase levels and reduced haemoglobin levels

http://dvntejaswinirollno40.blogspot.com/2023/03/20-yr-old-female-with-headcahe-and-neck.html